Research details: I am a graduate student, currently in the middle of my second year in the Singharoy lab. My work involves utilizing molecular dynamics to design bioenergetic protein supercomplexes, in order to investigate its effects on energy transfer within the electron transport chain. Specifically, I am targeting an unknown conformation of a hinge-protein within a mitochondrial protein supercomplex in yeast, which is known to be a key factor in electron transport. Decrypting the mechanistic advantages of supercomplex formation, as well as the function of this hinge-protein may ultimately lead to the construction of more efficient artificial energy systems.
- Presented at the International Society on Oxygen Transport to Tissue (ISOTT) - Title of the talk was "Molecular origins of ROS formation revealed by hybrid modeling of CIII-CIV supercomplexes"
- "Comparisons of Electron Transfer Reactions in a Cyanobacterial Tetrameric and Trimeric Photosystem I Complexes". Photochemistry and Photobiology. DOI: https://doi.org/10.1111/php.12886
- "Physiological and evolutionary implications of tetrameric photosystem I in cyanobacteria". Nature Plants. DOI: https://doi.org/10.1038/s41477-019-0566-x
- "Atoms to Phenotypes: Molecular Design Principles of Cellular Energy Metabolism". Cell. DOI: https://doi.org/10.1016/j.cell.2019.10.021
- "PSI-SMALP, a Detergent-free Cyanobacterial Photosystem I, Reveals Faster Femtosecond Photochemistry". Biophysical Journal. DOI: https://doi.org/10.1016/j.bpj.2019.11.3391
- 2019 - Duane F. Bruley Award from International Society on Oxygen Transport to Tissue (ISOTT)
- Western Photosynthesis Conference 2016 - "Best Undergraduate Poster"