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Project 3: Tissue-wide identification of novel regeneration factors using a new genetic tool: DUAL control; a tissue specific, temporally controlled genetic ablation system

  • How does epigenetic regulation contribute to regeneration? A rapid and sensitive genome-wide screen of epigenetic and chromosome structure regulators using DUAL control.
  • What are the function of these genes specifically in regenerating tissue? In vivo analysis of gene function using DUAL control.
  • How does alteration of organ wide properties affect regeneration? Manipulation of higher order properties, and their disc-wide influence on regeneration